Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 116
interventional 76
Observational 33
Registry 7

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 34
Drug|placebo 18
Device 5
Procedure 5
Other 4
Biological 2
Biological|placebo 2
Behavioral 1
Device|Drug 1
Dietary Supplement 1
Dietary Supplement|Drug 1
Drug|Procedure 1
placebo|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 26
China 6
NA 4
France 3
Korea, Republic of 2
Taiwan 2
United Kingdom 2
United States|Austria|Canada|United Kingdom 2
United States|Canada 2
Australia 1
Austria|Germany 1
Austria|Germany|Norway 1
Belgium 1
Canada 1
Denmark 1
Dominican Republic 1
Egypt 1
Germany 1
Iran, Islamic Republic of 1
Japan 1
Kazakhstan 1
Mexico 1
Singapore 1
Thailand 1
United States|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Chile|Denmark|Estonia|Finland|France|Germany|Hong Kong|Hungary|Israel|Italy|Korea, Republic of|Lithuania|Mexico|Netherlands|New Zealand|Poland|Portugal|Serbia|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|Denmark|Finland|France|Germany|Israel|Italy|Japan|New Zealand|Spain|Switzerland|United Kingdom 1
United States|Australia|Austria|Belgium|Canada|France|Germany|Netherlands|Spain|United Kingdom 1
United States|Australia|Canada|France|Germany|Italy|Japan|Poland|Spain|United Kingdom 1
United States|Belgium|Canada|Denmark|Germany|Italy|Netherlands|Spain|Sweden|United Kingdom 1
United States|Belgium|Canada|Germany|Greece|Israel|Italy|Spain|United Kingdom 1
United States|Canada|Germany|Poland|Russian Federation|United Kingdom 1
United States|Canada|United Kingdom 1
United States|France|Germany|Spain|United Kingdom 1
United States|France|Netherlands|United Kingdom 1
United States|Italy 1
United States|Puerto Rico 1

Sites per Study

Site_count Study_Count
1 44
2 3
3 4
4 1
6 1
7 1
9 4
11 1
12 3
16 1
23 1
24 2
26 1
28 1
35 1
38 1
61 1
66 1
75 1
86 1
176 1
180 1

Phase

Phase Study_Count
Phase 2 24
N/A 20
Phase 1 17
Phase 3 5
Phase 1/Phase 2 4
Phase 4 3
Phase 2/Phase 3 2
Early Phase 1 1

Number of Arms

Number_of_Arms Count_of_Studies
1 25
2 31
3 9
4 7
5 1
NA 3

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 25 17.00 6.00000 10.00 2.000 102 30 111.0000
1st Qu. 25 39.00 10.00000 13.75 29.250 114 34 155.5000
Median 25 92.50 19.00000 17.50 59.500 126 51 200.0000
Mean 25 95.95 28.76471 25.25 68.125 126 163 246.3333
3rd Qu. 25 108.00 27.00000 29.00 79.250 138 300 314.0000
Max. 25 320.00 200.00000 56.00 235.000 150 400 428.0000

Trial Group Type

group_type Group_Count
Experimental 83
Active Comparator 27
Placebo Comparator 26
Other 6
No Intervention 5
NA 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 42
Single Group Assignment 30
Sequential Assignment 3
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 62
Prevention 5
Diagnostic 4
Basic Science 3
Health Services Research 1
Other 1

Observational Studies

Studies by Country

Country Study_Count
United States 10
China 4
France 3
Sweden 3
Austria 2
Germany 2
United Kingdom 2
Japan 1
Netherlands|United Kingdom 1
United States|Canada 1
United States|Canada|Netherlands|Norway 1
United States|Egypt|Germany|Peru|Singapore 1
United States|France|Italy 1
United States|Japan 1

Sites per Study

Site_count Study_Count
1 21
2 5
4 1
5 3
6 1
26 1
36 1

Enrollment Metrics

Measure Observational
Min 26.00
1st Qu 58.25
Median 130.50
Mean 290.00
3rd Qu 357.50
Max 1500.00

Observation Model

observational_model Study_Count
Cohort 23
Case-Control 4
NA 3
Case-Only 1
Case Control 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 18
Cross-Sectional 5
Retrospective 5
Other 4
NA 1

Registries

Studies by Country

Country Study_Count
Switzerland 2
United States 2
China 1
Ireland 1
Sweden 1

Sites per Study

Site_count Study_Count
1 5
7 1
15 1

Enrollment Metrics

Measure Registries
Min 65.0000
1st Qu 94.5000
Median 250.0000
Mean 945.4286
3rd Qu 557.0000
Max 5000.0000

Registry Model

observational_model Study_Count
Cohort 4
Case-Control 1
Case-Only 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 7

Follow-up

target_duration Study_Count
5 Years 2
1 Year 1
2 Years 1
20 Years 1
30 Days 1
60 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04060147 Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis https://ClinicalTrials.gov/show/NCT04060147 Recruiting Gilead Sciences 2021-06-30
NCT03710122 Vancomycin for Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03710122 Recruiting Mayo Clinic 2022-05-31
NCT03359174 An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03359174 Recruiting Yale University 2020-12-01
NCT03333928 A POC and Dose-Ranging Study of HTD1801 in PSC Patients https://ClinicalTrials.gov/show/NCT03333928 Active, not recruiting HighTide Biopharma Pty Ltd 2020-04-30
NCT03183570 Detection of Integrin avb6 in Idiopathic Pulmonary Fibrosis and Primary Sclerosing Cholangitis Using PET/CT https://ClinicalTrials.gov/show/NCT03183570 Recruiting Stanford University 2021-04-14
NCT03124108 Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic Acid https://ClinicalTrials.gov/show/NCT03124108 Completed Genfit 2018-10-31
NCT03112681 Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT03112681 Active, not recruiting Zydus Discovery DMCC 2020-08-31
NCT03104582 Best Biliary Drainage Option in Advanced Klatskin Tumor https://ClinicalTrials.gov/show/NCT03104582 Completed Hepatopancreatobiliary Surgery Institute of Gansu Province 2017-07-14
NCT03104569 Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma https://ClinicalTrials.gov/show/NCT03104569 Recruiting Hepatopancreatobiliary Surgery Institute of Gansu Province 2021-04-01
NCT03087656 Antibiotics to Decrease Post ERCP Cholangitis https://ClinicalTrials.gov/show/NCT03087656 Recruiting University of Southern California 2021-02-23
NCT03069976 “Overlap Syndrome and PSC: Evaluating Role of Gut Microflora and Its Identification With Antibiotics in Children” https://ClinicalTrials.gov/show/NCT03069976 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2020-12-31
NCT02997878 A Single-arm,Phase IIa,Safety and Efficacy Trial of Selected MSCs in the Treatment of Patients With PSC & AiH https://ClinicalTrials.gov/show/NCT02997878 Recruiting University of Birmingham 2021-12-31
NCT02978339 A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT02978339 Completed Mayo Clinic 2018-11-16
NCT02967926 Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy https://ClinicalTrials.gov/show/NCT02967926 Completed Chulalongkorn University 2016-10-31
NCT02966834 Dose Response Study of GSK2330672 for the Treatment of Pruritus in Patients With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT02966834 Completed GlaxoSmithKline 2020-04-15
NCT02943460 Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Sclerosing Cholangitis Without Cirrhosis https://ClinicalTrials.gov/show/NCT02943460 Completed Gilead Sciences 2018-02-28
NCT02943447 Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis https://ClinicalTrials.gov/show/NCT02943447 Completed Gilead Sciences 2018-07-27
NCT02936596 Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome https://ClinicalTrials.gov/show/NCT02936596 Recruiting West China Hospital 2020-06-01
NCT02884557 NKT Role in the Regulation of the Inflammatory Bowel Disease https://ClinicalTrials.gov/show/NCT02884557 Recruiting University Hospital, Lille 2021-09-30
NCT02797665 Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids https://ClinicalTrials.gov/show/NCT02797665 Active, not recruiting Peking Union Medical College Hospital 2019-04-30
NCT02712736 Quality of Life in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02712736 Completed Duke University 2018-09-22
NCT02704364 Phase 2 Study of NGM282 in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02704364 Completed NGM Biopharmaceuticals, Inc 2017-06-30
NCT02653625 PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02653625 Completed Tobira Therapeutics, Inc. 2017-08-31
NCT02594891 Effect of 8.5 F Plastic Stent Without Proximal Flap on Prevention of Post-ERCP Cholangitis https://ClinicalTrials.gov/show/NCT02594891 Completed First People’s Hospital of Hangzhou 2016-02-29
NCT01824186 Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy https://ClinicalTrials.gov/show/NCT01824186 Completed National University Hospital, Singapore 2012-10-31
NCT02516605 A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients https://ClinicalTrials.gov/show/NCT02516605 Completed Novartis 2018-08-02
NCT02464020 A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02464020 Completed University of Minnesota 2017-05-01
NCT02446665 Disease Status in Primary Sclerosing Cholangitis by Elastography https://ClinicalTrials.gov/show/NCT02446665 Active, not recruiting University Health Network, Toronto 2019-12-31
NCT02424175 Fecal Microbiota Transplantation for the Treatment of Primary Sclerosing Cholangitis. https://ClinicalTrials.gov/show/NCT02424175 Completed Brigham and Women’s Hospital 2017-08-30
NCT02308111 Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT02308111 Recruiting Intercept Pharmaceuticals 2024-12-31
NCT02239211 A Trial of BTT1023 in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02239211 Completed University of Birmingham 2018-10-23
NCT02177136 Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT02177136 Completed Intercept Pharmaceuticals 2017-03-07
NCT02137668 Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin https://ClinicalTrials.gov/show/NCT02137668 Recruiting Sacramento Pediatric Gastroenterology 2018-05-31
NCT02098486 Comparisons of Intravenous Ceftriaxone With Intravenous Moxifloxacin in ERCP https://ClinicalTrials.gov/show/NCT02098486 Completed Kangbuk Samsung Hospital 2015-09-30
NCT02070627 Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy – Use in Acute Cholecystitis Sub-Study https://ClinicalTrials.gov/show/NCT02070627 Completed Ohio State University 2014-08-31
NCT02061540 Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02061540 Completed Mirum Pharmaceuticals, Inc. 2016-02-29
NCT01988506 Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases https://ClinicalTrials.gov/show/NCT01988506 Recruiting Assistance Publique - Hôpitaux de Paris 2020-08-13
NCT01879735 Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT https://ClinicalTrials.gov/show/NCT01879735 Completed University of Aarhus 2014-09-30
NCT01802073 Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating Effects https://ClinicalTrials.gov/show/NCT01802073 Completed Stanford University 2015-08-31
NCT01755507 Norursodeoxycholic Acid in the Treatment of Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01755507 Completed Dr. Falk Pharma GmbH 2015-10-31
NCT01744847 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study https://ClinicalTrials.gov/show/NCT01744847 Completed Soon Chun Hyang University 2012-08-31
NCT01695174 A Pilot Study of Xifaxan to Treat Patients With PSC https://ClinicalTrials.gov/show/NCT01695174 Completed Mayo Clinic 2013-12-31
NCT01672853 Simtuzumab (GS-6624) in the Prevention of Progression of Liver Fibrosis in Adults With Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT01672853 Completed Gilead Sciences 2016-08-08
NCT01456468 Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01456468 Completed Yale University 2014-06-30
NCT01322386 Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin https://ClinicalTrials.gov/show/NCT01322386 Completed Stanford University 2010-10-31
NCT04047160 Safety, Tolerability of OP-724 in Patients With Primary Biliary Cholangitis (Phase I) https://ClinicalTrials.gov/show/NCT04047160 Recruiting Komagome Hospital 2021-03-31
NCT04037007 Efficacy of Fistulotomy for Biliary Cannulation https://ClinicalTrials.gov/show/NCT04037007 Recruiting Coordinación de Investigación en Salud, Mexico 2020-03-03
NCT04006886 Gluten-free Diet in Patients With Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT04006886 Completed Universitätsklinikum Hamburg-Eppendorf 2019-05-09
NCT03995212 Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus https://ClinicalTrials.gov/show/NCT03995212 Recruiting Cara Therapeutics, Inc. 2021-01-31
NCT03890120 Safety, Tolerability, and Efficacy of Cilofexor in Non-Cirrhotic Adults With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03890120 Recruiting Gilead Sciences 2023-01-31
NCT03852836 Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts Images https://ClinicalTrials.gov/show/NCT03852836 Recruiting IHU Strasbourg 2021-02-28
NCT03754491 The Comparisons of One-stage Stone Removal in Mild and Moderate Cholangitis https://ClinicalTrials.gov/show/NCT03754491 Recruiting Chang Gung Memorial Hospital 2020-05-31
NCT03742973 A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCA https://ClinicalTrials.gov/show/NCT03742973 Completed Eli Lilly and Company 2019-09-26
NCT03722576 Vidofludimus Calcium for Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03722576 Recruiting Mayo Clinic 2020-10-31
NCT03716232 Kaffes Stent in the Management of Post-surgical Biliary Strictures https://ClinicalTrials.gov/show/NCT03716232 Recruiting Cairo University 2020-07-31
NCT03668145 Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT03668145 Recruiting Xijing Hospital of Digestive Diseases 2019-12-31
NCT03665519 Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT03665519 Active, not recruiting National Scientific Medical Center, Kazakhstan 2020-09-30
NCT03561584 Sulfasalazine for the Treatment of Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03561584 Recruiting Brigham and Women’s Hospital 2020-07-01
NCT03516006 Umbilical Cord Mesenchymal Stem Cells in Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT03516006 Active, not recruiting Fuzhou General Hospital 2019-01-31
NCT03422042 Short Duration Versus Fourteen Days Antibiotic in Common Bile Duct Cholangitis https://ClinicalTrials.gov/show/NCT03422042 Completed Prince of Songkla University 2019-02-20
NCT01148693 Gentamicin in Preventing Post Endoscopic Retrograde Cholangiopancreatography (ERCP) Cholangitis in Non-calculus Stenting https://ClinicalTrials.gov/show/NCT01148693 Completed Tehran University of Medical Sciences 2010-12-31
NCT01088607 Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01088607 Completed University of Tennessee 2016-12-31
NCT01085760 A Pilot Study of Vancomycin or Metronidazole in Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01085760 Completed Mayo Clinic 2011-11-30
NCT00955149 Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT00955149 Completed Mayo Clinic 2013-04-30
NCT03394924 A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT03394924 Completed Enanta Pharmaceuticals 2019-12-19
NCT03226067 Study to Assess Safety and Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid. https://ClinicalTrials.gov/show/NCT03226067 Completed Genkyotex SA 2019-04-11
NCT03099603 A Study of HTD1801 in Healthy Subjects https://ClinicalTrials.gov/show/NCT03099603 Completed HighTide Biopharma Pty Ltd 2017-07-11
NCT02705638 Treatment of IgG4-Related Disease With Revlimid and Rituximab https://ClinicalTrials.gov/show/NCT02705638 Completed Mayo Clinic 2019-04-30
NCT03872921 norUrsodeoxycholic Acid vs Placebo in PSC https://ClinicalTrials.gov/show/NCT03872921 Recruiting Dr. Falk Pharma GmbH 2021-04-30
NCT00630942 Minocycline in Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT00630942 Completed Mayo Clinic 2007-05-31
NCT00591968 Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community https://ClinicalTrials.gov/show/NCT00591968 Completed Edward Via Virginia College of Osteopathic Medicine 2008-03-31
NCT00325013 Evaluation of DHA for the Treatment of PSC https://ClinicalTrials.gov/show/NCT00325013 Completed Beth Israel Deaconess Medical Center 2012-05-31
NCT00166868 Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy https://ClinicalTrials.gov/show/NCT00166868 Completed National Taiwan University Hospital 2012-01-31
NCT00059202 Trial of High-dose Urso in Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT00059202 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT00004762 Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT00004762 Completed Office of Rare Diseases (ORD) NA
NCT00004842 Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT00004842 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 1999-04-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04385147 Advanced Endoscopy During COVID-19 https://ClinicalTrials.gov/show/NCT04385147 Completed Al-Azhar University 2020-07-01
NCT03337074 Paternally Inherited Phenotypes in Cholestasis https://ClinicalTrials.gov/show/NCT03337074 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2020-04-30
NCT03322943 The Comparison About the Response of Ursodeoxycholic Acid in Primary Biliary Cholangitis Only and Primary Biliary Cholangitis With High Immune Globulin G or Aminotransferase at West China Hospital https://ClinicalTrials.gov/show/NCT03322943 Completed West China Hospital 2018-12-30
NCT03188146 Performance of Scoring Systems in Chinese Patients With Primary Biliary Cholangitis (PBC) on Ursodeoxycholic Acid https://ClinicalTrials.gov/show/NCT03188146 Recruiting Humanity and Health Research Centre 2027-05-01
NCT03041662 Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT03041662 Completed Karolinska University Hospital 2016-10-31
NCT02917408 Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital https://ClinicalTrials.gov/show/NCT02917408 Completed West China Hospital 2017-01-31
NCT02659696 Nalfurafine Hydrochloride for Pruritus in Patients With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT02659696 Completed Teikyo University 2017-12-31
NCT02616705 Bile Usefulness for Detecting IgG4-related Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT02616705 Recruiting Mayo Clinic 2020-11-30
NCT02932449 A 5-year Longitudinal Observational Study of Patients With Primary Biliary Cholangitis https://ClinicalTrials.gov/show/NCT02932449 Active, not recruiting Target PharmaSolutions, Inc. 2021-09-30
NCT02545309 Secondary Sclerosing Cholangitis in Critically Ill Patients https://ClinicalTrials.gov/show/NCT02545309 Recruiting Medical University of Graz 2022-01-31
NCT02543957 Factors Associated With Increased Risk of Bacteremia and Cholangitis in ERCP With Cholangioscopy https://ClinicalTrials.gov/show/NCT02543957 Recruiting Baylor College of Medicine 2020-09-30
NCT02247934 Development of a Patient-Reported Outcome Measure to Assess Symptoms in Patients With Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT02247934 Completed Gilead Sciences 2015-10-31
NCT01819766 Detection of Advanced Colorectal Neoplasia by Stool DNA in Inflammatory Bowel Disease https://ClinicalTrials.gov/show/NCT01819766 Completed Exact Sciences Corporation 2017-01-31
NCT01798953 Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01798953 Completed Sahlgrenska University Hospital, Sweden 2013-02-28
NCT01556412 Endoscopic Ultrasound as an Early Diagnostic Tool for Primary Sclerosing Cholangitis https://ClinicalTrials.gov/show/NCT01556412 Completed Tischendorf, Jens, M.D. 2012-05-31
NCT04173286 Is Short Antibiotherapy Duration After Drainage Suitable for Patients Admitted in Intensive Care Medicine With a Severe Acute Cholangitis? https://ClinicalTrials.gov/show/NCT04173286 Recruiting Nantes University Hospital 2020-01-01
NCT03951324 Volumetric Laser Endomicroscopy’s (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study https://ClinicalTrials.gov/show/NCT03951324 Enrolling by invitation Innovative Digestive Health Education and Research Inc 2019-12-31
NCT03831529 Outcomes of Elderly Patients Admitted to the Intensive Care Unit With Severe Acute Cholangitis https://ClinicalTrials.gov/show/NCT03831529 Completed Central Hospital, Nancy, France 2018-11-14
NCT03809559 Repeatability and Reproducibility of Quantitative MRCP https://ClinicalTrials.gov/show/NCT03809559 Completed Perspectum Diagnostics Ltd 2018-09-08
NCT03766035 Cholangioscopy in Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT03766035 Recruiting Boston Scientific Corporation 2021-09-30
NCT03743272 Repeatability and Reproducibility of Multiparametric MRI https://ClinicalTrials.gov/show/NCT03743272 Recruiting Perspectum Diagnostics Ltd 2020-05-17
NCT03703076 A Post-Authorisation Non-Interventional Observational of Patients in France With Primary Biliary Cholangitis Treated With Obeticholic Acid in Real Life https://ClinicalTrials.gov/show/NCT03703076 Recruiting Intercept Pharma France SAS 2019-04-30
NCT03566797 Secondary Sclerosis Cholangitis Prospective https://ClinicalTrials.gov/show/NCT03566797 Recruiting Medical University of Graz 2021-06-01
NCT03545672 Early Identification of Myocardial Impairment in PBC https://ClinicalTrials.gov/show/NCT03545672 Completed RenJi Hospital 2019-02-01
NCT01161992 Genomics of Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT01161992 Active, not recruiting Mayo Clinic 2025-12-31
NCT01003782 Routine Bile Collection for Microbiological Analysis During Cholangiography https://ClinicalTrials.gov/show/NCT01003782 Completed Hannover Medical School 2009-02-28
NCT00951327 Cholangioscopy Using Narrow Band Imaging (NBI) in Patients With Primary Sclerosing Cholangitis (PSC) Undergoing Endoscopic Retrograde Cholangiopancreatogram (ERCP) https://ClinicalTrials.gov/show/NCT00951327 Completed Mayo Clinic 2010-08-31
NCT01556555 Clinical Utility of the Spyglass System in Primary Sclerosing Cholangitis (PSC) https://ClinicalTrials.gov/show/NCT01556555 Completed Karolinska University Hospital 2011-05-31
NCT01392274 pCLE For the Diagnosis Of Cancer in Unknown Bile Duct Stricture https://ClinicalTrials.gov/show/NCT01392274 Completed Mauna Kea Technologies 2013-09-30
NCT03178630 MRI Biomarkers in as Predictor of Clinical Endpoints in Pediatric Autoimmune Liver Disease https://ClinicalTrials.gov/show/NCT03178630 Recruiting Children’s Hospital Medical Center, Cincinnati 2030-02-28
NCT03175471 MRI Based Biomarkers in Pediatric Autoimmune Liver Disease https://ClinicalTrials.gov/show/NCT03175471 Recruiting Children’s Hospital Medical Center, Cincinnati 2021-01-30
NCT00587236 Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis https://ClinicalTrials.gov/show/NCT00587236 Completed Mayo Clinic 2010-08-31
NCT00179439 NPDT Evaluation in Children With CFTR and (PSC) https://ClinicalTrials.gov/show/NCT00179439 Completed Beth Israel Deaconess Medical Center 2006-01-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03146936 Swiss Primary Sclerosing Cholangitis Cohort Study https://ClinicalTrials.gov/show/NCT03146936 Recruiting Fondazione Epatocentro Ticino 2022-12-31
NCT03146910 Swiss Primary Biliary Cholangitis Cohort Study https://ClinicalTrials.gov/show/NCT03146910 Recruiting Fondazione Epatocentro Ticino 2022-12-31
NCT02736708 Registry Trial to Determine pCLE Image Interpretation Criteria and Preliminary Accuracy for PSC Biliary Strictures https://ClinicalTrials.gov/show/NCT02736708 Active, not recruiting University of Colorado, Denver 2018-12-31
NCT01880606 Endomicroscopy in Primary Sclerosing Cholangitis Related Inflammatory Bowel Disease Surveillance https://ClinicalTrials.gov/show/NCT01880606 Completed Karolinska University Hospital 2013-12-31
NCT03771547 ERCP in Super-aged Patients Considering Difficult Cannulation: Challenges and Adverse Events https://ClinicalTrials.gov/show/NCT03771547 Completed The Second Hospital of Nanjing Medical University 2018-01-30
NCT03610308 ESTES Snapshot Audit 2018 https://ClinicalTrials.gov/show/NCT03610308 Completed European Socierty for Trauma and Emergency Surgery 2018-12-31
NCT03445585 Biobank for Cholestatic Liver Diseases. https://ClinicalTrials.gov/show/NCT03445585 Enrolling by invitation Mayo Clinic 2030-01-31